Kadcyla Trastuzumab Emtansine 160mg Injection
Introduction: Kadcyla Trastuzumab Emtansine 160mg Injection is an advanced targeted therapy used primarily for the treatment of HER2-positive metastatic breast cancer. It combines the HER2-targeting properties of trastuzumab with the cytotoxic agent emtansine, delivering chemotherapy directly to cancer cells while minimizing effects on healthy tissue.
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📞 Phone: +91 9730316395
📧 Email: info@globmedindia.com
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Composition and Content
- Trastuzumab – a monoclonal antibody targeting HER2 receptors on cancer cells.
- Emtansine (DM1) – a cytotoxic agent linked to trastuzumab that interferes with microtubule formation, inhibiting cancer cell growth.
- Excipients – includes buffers and stabilizers to maintain solution stability.
How to Use & Doses
- Administration: Intravenous infusion by a healthcare professional.
- Typical Dose: 3.6 mg/kg body weight every 3 weeks.
- Infusion Duration: Usually 30–90 minutes depending on patient tolerance.
- Monitoring: Regular heart function tests (ECHO or MUGA scan), liver function tests, and complete blood counts are recommended.
Uses & Treatments
- Treatment of HER2-positive metastatic breast cancer.
- Can be used in patients previously treated with trastuzumab and taxane chemotherapy.
- May be considered for adjuvant therapy in specific clinical scenarios.
Advantages
- Targeted delivery of chemotherapy reduces systemic toxicity.
- Improves survival rates and progression-free intervals in HER2-positive patients.
- Combines efficacy of trastuzumab with potent cytotoxic action in a single therapy.
Storage Conditions
- Store in a refrigerator at 2°C to 8°C.
- Protect from light.
- Do not freeze.
- Use immediately after preparation or follow manufacturer guidelines for stability.
Alternative Indian Brands
- Kadcyla Trastuzumab Emtansine biosimilars are available in India under various brand names, including:
- Trastem 160 mg
- Emtastra 160 mg
- KADCELL 160 mg
