Temotero Temozolomide 20 mg Capsules
Temotero Temozolomide 20 mg Capsules is an oral chemotherapy medicine used primarily in the treatment of certain types of brain cancers. It contains Temozolomide, an alkylating agent that works by damaging the DNA of cancer cells, thereby preventing their growth and multiplication. This medication is commonly prescribed for patients diagnosed with Glioblastoma Multiforme and Anaplastic Astrocytoma.
Temotero is widely used as part of combination therapy alongside radiation or as a maintenance treatment depending on the stage and severity of the disease. It is known for its effectiveness and convenience as an oral capsule compared to injectable chemotherapy.
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Composition and Content
- Active Ingredient: Temozolomide – 20 mg
- Form: Oral Capsules
- Class: Alkylating Antineoplastic Agent
How to Use
- Take the capsule orally with a glass of water, preferably on an empty stomach.
- Do not open, crush, or chew the capsule.
- Follow your oncologist’s instructions strictly regarding timing and duration.
- It is usually taken once daily in cycles (e.g., 5 days on, followed by 23 days off).
Dosage
- Dosage varies depending on:
- Body surface area (BSA)
- Type of cancer
- Treatment phase (initial or maintenance)
- Typical dosing:
- 75 mg/m² daily during radiotherapy
- 150–200 mg/m² for maintenance cycles
- Always consult a healthcare professional for personalized dosage.
Uses
Temotero Temozolomide 20 mg Capsules are used in:
- Treatment of Glioblastoma Multiforme (GBM)
- Treatment of Anaplastic Astrocytoma
- Other off-label brain tumor therapies as advised by oncologists
Treatments & Mechanism
Temozolomide works by:
- Alkylating/methylating DNA in cancer cells
- Triggering cell death (apoptosis)
- Slowing tumor growth and spread
It is often used:
- Alongside radiotherapy (concurrent phase)
- As maintenance chemotherapy
Advantages
- Oral administration (no need for hospitalization)
- Proven effectiveness in brain tumors
- Better patient compliance compared to IV chemotherapy
- Can cross the blood-brain barrier efficiently
- Flexible dosing schedules
Storage Conditions
- Store at room temperature (15°C to 30°C)
- Keep away from moisture and direct sunlight
- Store in original packaging
- Keep out of reach of children
Alternative Indian Brands for Temozolomide 20 mg
Some commonly available alternatives in India include:
- Temodal Capsules (by Sun Pharmaceutical Industries)
- Temonat Capsules (by Natco Pharma)
- Temozol Capsules (various manufacturers)
- Temokem Capsules
- Temcad Capsules
(Availability may vary based on region and supplier.)
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