RITUXIREL Rituximab 500 mg Injection
RITUXIREL Rituximab 500 mg Injection is a targeted anti-cancer and immunotherapy medication containing Rituximab. It belongs to a class of drugs known as monoclonal antibodies, specifically designed to target CD20 proteins found on the surface of certain B-cells (a type of white blood cell).
By binding to these CD20-positive cells, Rituximab helps the immune system identify and destroy abnormal or cancerous B-cells. This makes it highly effective in treating various blood cancers and autoimmune disorders.
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Composition and Content
- Active Ingredient: Rituximab
- Strength: 500 mg per vial
- Form: Sterile solution for intravenous infusion
- Class: Anti-CD20 monoclonal antibody
How to Use
- Administered intravenously (IV infusion) under strict medical supervision.
- Given in a hospital or oncology clinic setting.
- Pre-medications (like antihistamines, paracetamol, or steroids) are often given to reduce infusion reactions.
- Infusion duration may vary from a few hours depending on tolerance.
Dosage
- Dosage depends on:
- Patient’s body surface area (BSA)
- Type of disease being treated
- Treatment protocol (monotherapy or combination therapy)
Typical Regimens:
- Lymphoma: 375 mg/m² per cycle
- Rheumatoid Arthritis: 1000 mg IV on Day 1 and Day 15
- Maintenance Therapy: Every 2–6 months depending on condition
Always follow the oncologist’s prescribed dosage.
Uses
RITUXIREL Rituximab is widely used for:
Cancer Treatments:
- Non-Hodgkin’s Lymphoma (NHL)
- Chronic Lymphocytic Leukemia (CLL)
Autoimmune Disorders:
- Rheumatoid Arthritis
- Granulomatosis with Polyangiitis (GPA)
- Microscopic Polyangiitis (MPA)
Treatments & Therapeutic Benefits
- Targets only abnormal B-cells, sparing healthy cells
- Enhances immune response against cancer cells
- Often combined with chemotherapy (e.g., R-CHOP regimen)
- Provides long-term remission in many cases
Advantages
- Targeted Therapy: Precision action on CD20 cells
- Effective: Proven results in blood cancers
- Versatile: Used in both oncology and autoimmune diseases
- Improves Survival Rates in lymphoma patients
- Reduces Disease Progression
Storage Conditions
- Store at 2°C to 8°C (refrigerated)
- Do not freeze
- Protect from light
- Keep in original packaging
- Use immediately after dilution (as per hospital protocol)
Alternative Indian Brands for Rituximab 500 mg Injection
Here are some trusted Indian alternatives to RITUXIREL:
- Reditux – by Dr. Reddy’s Laboratories
- Ristova – by Intas Pharmaceuticals
- MabThera – by Roche
- Rituxan – widely used internationally
These brands offer similar efficacy and are commonly exported globally.
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