Palnat Palbociclib 100 mg Capsules
Palnat Palbociclib 100 mg Capsules contain Palbociclib, a targeted anti-cancer medicine used primarily in the treatment of hormone receptor-positive (HR+), HER2-negative breast cancer. It belongs to a class of drugs known as CDK4/6 inhibitors, which work by slowing or stopping the growth of cancer cells by blocking proteins responsible for cell division.
Palnat is commonly prescribed in combination with hormonal therapies to improve treatment outcomes and delay disease progression in advanced or metastatic breast cancer patients.
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Composition and Content
- Active Ingredient: Palbociclib – 100 mg
- Form: Oral Capsules
- Packaging: Typically available in blister packs or bottles (as per manufacturer)
How to Use
- Take the capsule orally with or without food, preferably at the same time each day.
- Swallow whole with water; do not crush or chew.
- Usually taken in combination with hormonal therapy such as letrozole or fulvestrant.
- Follow your oncologist’s prescription strictly.
Dosage
- Standard regimen:
- 125 mg once daily for 21 days, followed by 7 days off (28-day cycle)
- Your doctor may adjust dose to 100 mg or 75 mg based on tolerance
- Palnat 100 mg is often prescribed as a dose-adjusted option
⚠️ Dosage must be individualized based on patient condition and side effects.
Uses
- Treatment of HR-positive, HER2-negative advanced breast cancer
- Used in combination with:
- Aromatase inhibitors (e.g., letrozole)
- Fulvestrant in disease progression cases
Treatments & Mechanism
Palbociclib works by:
- Inhibiting Cyclin-Dependent Kinases (CDK) 4 and 6
- Blocking cancer cell cycle progression from G1 to S phase
- Slowing tumor growth and improving survival outcomes
Advantages
- Targeted therapy with higher precision
- Helps delay cancer progression
- Improves effectiveness of hormonal therapy
- Oral administration (no hospitalization required)
- Better tolerated compared to traditional chemotherapy
Storage Conditions
- Store at room temperature (20°C–25°C)
- Keep away from moisture and direct sunlight
- Keep out of reach of children
- Do not use expired capsules
Recommended Indian Alternative Brands
Some widely used alternatives to Palnat include:
- Palbace (Cipla)
- Palbonix (Beacon Pharmaceuticals)
- Palbocent (Hetero Healthcare)
- Palbociclib by Natco Pharma
- Paleno (Dr. Reddy’s Laboratories)
These brands offer similar efficacy and are often more cost-effective depending on availability.
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