Lorbriqua Lorlatinib 100 mg Tablets
Lorbriqua (Lorlatinib) 100 mg Tablets is an advanced targeted anti-cancer medication used primarily for the treatment of non-small cell lung cancer (NSCLC) that is ALK-positive (anaplastic lymphoma kinase mutation). It belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs), designed to block abnormal proteins that promote cancer cell growth.
Lorlatinib is especially effective in patients who have developed resistance to earlier ALK inhibitors, making it a next-generation therapy with strong central nervous system (CNS) penetration—helping treat or prevent brain metastases.
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Composition and Content
- Active Ingredient: Lorlatinib 100 mg
- Form: Oral tablets
- Packaging: Usually supplied in blister packs or bottles (as per manufacturer)
How to Use
- Take the tablet orally once daily, with or without food
- Swallow whole with water; do not crush or chew
- Take at the same time every day for best results
- Follow the oncologist’s prescription strictly
Dosage
- Standard Dose: 100 mg once daily
- Dose adjustments may be required based on:
- Side effects
- Liver function
- Drug interactions
⚠️ Never self-adjust the dose without medical supervision.
Uses
Lorbriqua is prescribed for:
- ALK-positive metastatic NSCLC
- Patients who have:
- Progressed after other ALK inhibitors like Crizotinib or Alectinib
- Treatment of brain metastases in lung cancer
Treatment Benefits
- Targets specific cancer mutations (precision therapy)
- Effective in resistant cancer cases
- Strong penetration into the brain
- Improves progression-free survival
Advantages
- Oral therapy (no hospitalization required)
- Advanced generation ALK inhibitor
- Better CNS activity compared to earlier drugs
- Convenient once-daily dosing
Storage Conditions
- Store at room temperature (20°C–25°C)
- Keep away from moisture and direct sunlight
- Keep out of reach of children
- Do not use expired medication
Alternative Indian Brands for Lorlatinib 100 mg
Some cost-effective Indian alternatives include:
- Lorlatinib by Natco Pharma
- Lorlatinib by Hetero Healthcare
- Lorlatinib by Dr. Reddy's Laboratories
These generics offer similar efficacy at more affordable pricing for global patients.
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