JAKAVI Ruxolitinib 5 MG Tablets
Ruxolitinib 5 mg Tablets (brand: JAKAVI) are prescription anti-cancer medicines used primarily to treat certain blood disorders and cancers. These tablets belong to a class of drugs known as Janus kinase (JAK) inhibitors, which work by blocking specific enzymes (JAK1 and JAK2) responsible for abnormal blood cell production and inflammation.
Ruxolitinib helps regulate the immune system and slows down the growth of abnormal cells, making it highly effective in managing diseases like myelofibrosis and polycythemia vera.
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Composition and Content
- Active Ingredient: Ruxolitinib
- Strength: 5 mg per tablet
- Form: Oral tablets
- Class: JAK (Janus kinase) inhibitor
How to Use
- Take the tablet orally with or without food, as prescribed by your doctor
- Swallow whole with water (do not crush or chew)
- Follow a fixed schedule for best results
- Regular blood tests are required during treatment
Dosage
- Dosage depends on:
- Patient’s condition
- Platelet count
- Response to therapy
Common starting dose:
- 5 mg twice daily (may be adjusted by doctor)
⚠️ Never adjust dose without medical advice.
Uses
JAKAVI Ruxolitinib 5 mg is used for:
- Myelofibrosis (MF)
- Polycythemia Vera (PV) (especially when hydroxyurea is not effective)
- Graft-versus-host disease (GVHD)
- Certain bone marrow disorders
Treatments & Mechanism
Ruxolitinib works by:
- Blocking JAK1/JAK2 pathways
- Reducing inflammation and abnormal blood cell production
- Improving symptoms like:
- Enlarged spleen
- Fatigue
- Night sweats
- Weight loss
Advantages
- Targeted therapy with better precision than chemotherapy
- Helps reduce spleen size significantly
- Improves overall quality of life
- Effective for patients resistant to other treatments
- Oral administration (easy to take at home)
Storage Conditions
- Store at room temperature (20°C–25°C)
- Keep away from moisture and heat
- Store in original packaging
- Keep out of reach of children
Alternative Indian Brands of Ruxolitinib 5 mg
Some commonly available Indian alternatives include:
- Ruxolitib Tablets (Generic brands)
- Ruxocip (by Cipla)
- Ruxonat (by Natco Pharma)
- Ruxofin (by Dr. Reddy’s Laboratories)
- Jaknat (by Natco Pharma)
👉 Always consult your doctor before switching brands.
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