Flurasted 5 Fluorouracil 1 gm Injection
Flurasted 5 Fluorouracil 1 gm Injection is an anti-cancer chemotherapy medicine containing Fluorouracil. It is widely used in oncology for the treatment of several solid tumors. Fluorouracil belongs to the antimetabolite class and works by blocking DNA and RNA synthesis in rapidly dividing cancer cells, thereby slowing tumor growth and promoting cancer cell death. It is commonly used as part of combination chemotherapy regimens under strict medical supervision.
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Composition and Content
- Active Ingredient: Fluorouracil (5-FU) 1 gm
- Dosage Form: Injectable solution for IV use
- Drug Class: Antimetabolite (pyrimidine analog)
- Route: Intravenous (IV)
Mechanism of Action (Explanation)
Fluorouracil inhibits thymidylate synthase, an enzyme essential for DNA synthesis. This disruption prevents cancer cells from replicating, leading to cell death, especially in rapidly dividing tumors.
Uses and Indications
Flurasted 5 Fluorouracil Injection is used in the treatment of:
- Colorectal cancer
- Breast cancer
- Gastric (stomach) cancer
- Pancreatic cancer
- Head and neck cancers
It is commonly used in combination chemotherapy protocols.
Dosage and Administration
- Administered only by qualified healthcare professionals
- Dosage depends on:
- Body surface area (BSA)
- Type and stage of cancer
- Patient’s response and tolerance
- Given as IV bolus injection or continuous infusion
Important: Not for self-administration.
How to Use
- Administer intravenously under medical supervision.
- May be given as bolus or infusion depending on treatment plan.
- Requires regular blood count monitoring during therapy.
Advantages
- Widely used and clinically proven chemotherapy drug
- Effective against multiple solid tumors
- Works well in combination therapy
- Cost-effective cancer treatment option
Possible Side Effects
- Nausea and vomiting
- Diarrhea
- Mouth ulcers
- Bone marrow suppression
- Skin sensitivity to sunlight
Seek immediate medical attention if severe side effects occur.
Storage Conditions
- Store below 25°C
- Protect from light
- Do not freeze
- Keep out of reach of children
Alternative Indian Brands for Fluorouracil Injection
- 5-FU Injection IP (various Indian manufacturers)
- Fluorouracil Injection generic versions
- Adrucil
(Availability may vary depending on supplier and country regulations.)
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