Elaxim Recombinant Tissue Plasminogen Activator 40mg Injection
Elaxim Recombinant Tissue Plasminogen Activator (rtPA) 40mg Injection is a life-saving thrombolytic (clot-dissolving) medication used in emergency medical conditions caused by blood clots. It contains a recombinant form of tissue plasminogen activator, a naturally occurring protein that helps break down clots in blood vessels and restore normal blood flow.
This injection is primarily used in critical situations such as acute ischemic stroke, myocardial infarction (heart attack), and pulmonary embolism, where rapid clot dissolution is essential to prevent severe complications or death. Elaxim works by converting plasminogen into plasmin, an enzyme that dissolves fibrin clots effectively.
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Composition and Content
- Active Ingredient: Recombinant Tissue Plasminogen Activator (rtPA)
- Strength: 40 mg per vial
- Form: Lyophilized powder for injection (to be reconstituted before use)
- Class: Thrombolytic / Fibrinolytic agent
How to Use
- Administered intravenously (IV) by a trained healthcare professional.
- The powder is reconstituted with sterile water before administration.
- Given in a hospital setting with continuous monitoring.
- Dosage and infusion rate depend on the condition being treated.
Dosage
Dosage varies depending on the indication:
- Acute Ischemic Stroke: Weight-based dosing within a specific time window (usually within 3–4.5 hours of symptom onset)
- Myocardial Infarction (Heart Attack): Bolus followed by infusion
- Pulmonary Embolism: Infusion over a defined period
⚠️ Always administered under strict medical supervision. Self-administration is not allowed.
Uses
Elaxim 40mg Injection is used for:
- Acute ischemic stroke
- Acute myocardial infarction (heart attack)
- Pulmonary embolism
- Clearing blocked central venous catheters (in some cases)
Treatments Supported
- Emergency stroke management
- Cardiac emergency care
- Pulmonary vascular obstruction treatment
- Critical care and ICU interventions
Advantages
- Rapid clot dissolution and restoration of blood flow
- Reduces risk of long-term disability in stroke patients
- Minimizes heart muscle damage during heart attack
- Improves survival in life-threatening thrombotic conditions
- Highly targeted fibrin-specific action
Storage Conditions
- Store at 2°C to 8°C (refrigerated)
- Protect from light and moisture
- Do not freeze
- Use immediately after reconstitution or as per medical guidance
Alternative Indian Brands for rtPA Injection
Some commonly available alternatives in India include:
- Actilyse Injection (Alteplase)
- Alteplase Injection (various manufacturers)
- Thrombonorm Injection
- Alteplase Lyophilized Powder (generic versions)
👉 Availability may vary based on region and hospital supply.
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