Sigrima Pertuzumab 420 mg Injection
Sigrima Pertuzumab 420 mg Injection is a targeted anti-cancer medication used primarily in the treatment of HER2-positive breast cancer. It contains Pertuzumab, a monoclonal antibody that works by specifically targeting the HER2 receptors on cancer cells. By blocking these receptors, it prevents cancer cell growth and division, helping to slow or stop the progression of the disease.
Pertuzumab is often used in combination with other chemotherapy drugs and targeted therapies such as Trastuzumab to enhance treatment effectiveness. This combination therapy has significantly improved survival outcomes in patients with HER2-positive breast cancer.
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Composition and Content
- Active Ingredient: Pertuzumab
- Strength: 420 mg / 14 mL vial
- Form: Solution for intravenous infusion
- Drug Class: Monoclonal antibody (HER2 inhibitor)
How to Use
- Administered as an intravenous (IV) infusion under medical supervision.
- Usually given in a hospital or oncology clinic.
- Not for self-administration.
- Often used in combination with chemotherapy and HER2-targeted therapies.
Dosage
- Initial Dose: 840 mg IV infusion
- Maintenance Dose: 420 mg every 3 weeks
- Duration and regimen depend on patient condition and treatment response.
- Always follow the oncologist’s prescription.
Uses
Sigrima Pertuzumab 420 mg Injection is used for:
- HER2-positive metastatic breast cancer
- Early-stage HER2-positive breast cancer (neoadjuvant/adjuvant therapy)
- Recurrent breast cancer
Treatments (Combination Therapy)
Commonly used with:
- Trastuzumab
- Chemotherapy agents like docetaxel
- Targeted therapy regimens for advanced cancer care
Advantages
- Specifically targets cancer cells (precision therapy)
- Improves survival rates in HER2-positive patients
- Works synergistically with other therapies
- Reduces tumor growth and spread
- Well-studied and clinically proven treatment
Storage Conditions
- Store in a refrigerator at 2°C to 8°C
- Do not freeze
- Protect from light
- Keep in original packaging
- Use immediately after dilution (as per medical guidelines)
Alternative Indian Brands
Some alternative brands containing Pertuzumab include:
- Perjeta (by Roche)
- Biosimilar versions (availability may vary in India depending on approval and supplier)
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We specialize in supplying high-quality oncology drugs including Pertuzumab for the treatment of HER2-positive breast cancer.
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