Palnat Palbociclib 125 mg Capsules
Palnat Palbociclib 125 mg Capsules contain Palbociclib, a targeted anti-cancer medicine used primarily in the treatment of hormone receptor-positive (HR+), HER2-negative advanced or metastatic breast cancer. It belongs to a class of drugs known as CDK4/6 inhibitors, which work by slowing down or stopping the growth of cancer cells.
Palbociclib is usually prescribed in combination with hormonal therapies to improve treatment effectiveness and delay cancer progression. It is widely used as part of modern oncology protocols due to its targeted mechanism and improved patient outcomes.
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Composition and Content
- Active Ingredient: Palbociclib
- Strength: 125 mg per capsule
- Form: Oral Capsules
- Packaging: Typically available in blister packs or bottles (as per manufacturer)
How to Use
- Take the capsule orally with water, preferably at the same time each day.
- It can be taken with or without food.
- Do not crush, chew, or open the capsule.
- Follow your oncologist’s prescription strictly.
Dosage
- Standard dose: 125 mg once daily for 21 days, followed by 7 days off (28-day cycle).
- Dose adjustments may be required based on:
- Patient tolerance
- Side effects
- Blood count levels
Uses
Palnat Palbociclib is used in the treatment of:
- Advanced or metastatic breast cancer (HR+, HER2-)
- In combination with:
- Aromatase inhibitors (like letrozole)
- Fulvestrant (for disease progression cases)
Treatments & Mechanism
Palbociclib works by:
- Inhibiting Cyclin-Dependent Kinases 4 and 6 (CDK4/6)
- Blocking cancer cell division at a critical phase (G1 phase)
- Slowing tumor growth and improving survival outcomes
Advantages
- Targeted therapy with higher precision than traditional chemotherapy
- Helps delay disease progression
- Improves progression-free survival
- Can be combined effectively with hormone therapy
- Generally better tolerated compared to cytotoxic chemotherapy
Storage Conditions
- Store below 30°C in a dry place
- Keep away from direct sunlight and moisture
- Keep out of reach of children
- Do not use expired medication
Alternative Indian Brands for Palbociclib 125 mg
Some commonly available Indian alternatives include:
- Palbace (by Glenmark)
- Palbo (by MSN Laboratories)
- Palbonix (by Beacon Pharma)
- Palbocent (by Cipla)
- Palbocib (by Hetero Healthcare)
(Availability may vary; consult supplier or oncologist)
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