Stelera Ustekinumab 130 mg Injection
Stelera Ustekinumab 130 mg Injection is a biologic medication used to treat autoimmune and inflammatory conditions. It contains ustekinumab, a monoclonal antibody that targets specific proteins in the immune system (IL-12 and IL-23), helping to reduce inflammation and control disease progression. It is widely prescribed for conditions like psoriasis, psoriatic arthritis, and certain gastrointestinal disorders such as Crohn’s disease.
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Composition and Content
- Active Ingredient: Ustekinumab
- Strength: 130 mg per vial
- Form: Injectable solution (intravenous use)
- Drug Class: Monoclonal antibody / Immunosuppressant
Ustekinumab works by selectively blocking cytokines (IL-12 and IL-23), which play a key role in inflammatory and immune responses.
How to Use
- Administered intravenously (IV infusion) by a qualified healthcare professional.
- Usually given in a clinical or hospital setting.
- Followed by subcutaneous maintenance doses depending on the condition.
Dosage
- Initial dose is weight-based IV infusion (130 mg vial used accordingly).
- Maintenance doses are typically given every 8–12 weeks (subcutaneous injection).
- Dosage and frequency depend on:
- Body weight
- Disease severity
- Physician’s recommendation
Uses
Stelera Ustekinumab is used in the treatment of:
- Moderate to severe plaque psoriasis
- Psoriatic arthritis
- Crohn’s disease
- Ulcerative colitis
Treatment Benefits
- Reduces inflammation and immune overactivity
- Improves skin lesions in psoriasis
- Helps maintain remission in Crohn’s disease
- Enhances quality of life in chronic autoimmune disorders
Advantages
- Targeted therapy with fewer systemic side effects compared to traditional immunosuppressants
- Long dosing interval (every 8–12 weeks)
- Effective in patients not responding to conventional treatments
- Improves both physical symptoms and long-term disease control
Storage Conditions
- Store at 2°C to 8°C (refrigerated)
- Do not freeze
- Keep in original packaging to protect from light
- Do not shake the vial
- Use immediately after preparation (as advised by healthcare provider)
Alternative Indian Brands
Some alternative brands containing ustekinumab or similar biologics include:
- Stelara Injection (Original brand by Janssen)
- Ustecinumab Biosimilars (emerging in India depending on availability)
- Other biologics with similar indications (different molecules):
- Adalimumab
- Infliximab
(Note: Alternatives should only be used under medical supervision.)
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