PEMETREX Pemetrexed 100MG Injection
Pemetrexed 100MG Injection (marketed as PEMETREX) is a chemotherapy medication widely used in the treatment of various cancers, especially lung cancer and mesothelioma. It belongs to a class of drugs known as antifolate antineoplastic agents, which work by disrupting cancer cell growth and preventing them from multiplying.
This injection is typically administered under the supervision of an oncologist in a hospital or clinical setting. It is often used alone or in combination with other chemotherapy drugs depending on the type and stage of cancer.
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Composition and Content
- Active Ingredient: Pemetrexed Disodium
- Strength: 100 mg per vial
- Form: Lyophilized powder for injection (to be reconstituted before use)
- Category: Antifolate Chemotherapy Agent
How PEMETREX Pemetrexed Injection Works
Pemetrexed inhibits key enzymes required for DNA and RNA synthesis in cancer cells. By blocking these pathways, it prevents tumor growth and induces cancer cell death.
How to Use
- Administered as an intravenous (IV) infusion
- Given only by qualified healthcare professionals
- Usually infused over 10 minutes
- Patients may be prescribed folic acid and vitamin B12 supplements to reduce side effects
Dosage
- Dosage depends on:
- Body surface area (BSA)
- Type of cancer
- Patient’s overall health
- Common regimen:
- 500 mg/m² once every 21 days (cycle-based therapy)
- Always follow oncologist recommendations strictly
Uses and Treatments
PEMETREX Pemetrexed 100MG Injection is used for:
✔ Non-Small Cell Lung Cancer (NSCLC)
- First-line treatment (with cisplatin)
- Maintenance therapy
✔ Malignant Pleural Mesothelioma
- Often combined with platinum-based chemotherapy
Advantages
- Targeted action on cancer cell metabolism
- Effective in combination therapy
- Better tolerability compared to some traditional chemotherapies
- Proven survival benefit in lung cancer patients
Possible Side Effects
- Nausea and vomiting
- Fatigue
- Low blood cell counts (anemia, neutropenia)
- Mouth sores
- Skin rash
⚠️ Regular monitoring through blood tests is essential during treatment.
Storage Conditions
- Store below 25°C
- Keep in a dry and dark place
- Protect from light
- Keep out of reach of children
- Reconstituted solution should be used promptly or as directed
Alternative Indian Brands for Pemetrexed 100MG
Some commonly available Indian alternatives include:
- Pemnat 100 mg Injection
- Alimta (by Eli Lilly)
- Pemetrexed Fresenius Kabi
- Pemgem 100 mg Injection
- Pemetrexed Dr. Reddy’s
(Availability may vary based on region and export regulations)
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