💉 Doxorex (Doxorubicin 50 mg Injection)
🔷 Introduction
Doxorex 50 mg Injection contains doxorubicin hydrochloride, a powerful chemotherapy medicine used to treat a wide range of cancers. It belongs to the anthracycline class of anticancer drugs, known for stopping cancer cell growth by damaging their DNA.
It is widely used in hospitals and oncology centers under strict medical supervision.
🔬 Composition & Content
- Active Ingredient: Doxorubicin Hydrochloride
- Strength: 50 mg per vial
- Form: Sterile injectable solution (typically 2 mg/mL concentration)
- Class: Anthracycline antineoplastic agent
⚙️ Mechanism of Action
- Intercalates into DNA and blocks replication
- Inhibits topoisomerase II enzyme
- Generates free radicals → destroys cancer cells
💊 How to Use
- Administered intravenously (IV) by a qualified oncologist
-
Given as:
- Slow IV injection (3–10 minutes), OR
- IV infusion via central line
- Must NOT be self-administered
📏 Dosage
Dosage depends on cancer type, body surface area (BSA), and patient condition:
- Single agent: 60–75 mg/m² every 21 days
- Combination therapy: 40–75 mg/m² every 21–28 days
- Lifetime cumulative dose should not exceed 550 mg/m² (cardiotoxicity risk)
🏥 Uses & Treatments
Doxorex is used in the treatment of:
🎯 Major Cancer Types
- Breast cancer
- Lung cancer
- Ovarian cancer
- Bladder cancer
- Thyroid cancer
- Gastric cancer
🧬 Blood & Lymphatic Cancers
- Hodgkin lymphoma
- Non-Hodgkin lymphoma
- Acute lymphoblastic leukemia (ALL)
- Acute myeloid leukemia (AML)
- Multiple myeloma
✅ Advantages
- Broad-spectrum anticancer activity
- Highly effective in combination chemotherapy
- Proven and widely used globally
- Works on multiple cancer pathways
- Improves survival rates in many cancers
❄️ Storage Conditions
- Store at 2°C to 8°C (refrigerated)
- Protect from light
- Do not freeze
- If gel forms, allow to return to room temperature before use
🔄 Alternative Indian Brands of Doxorubicin Injection
Some commonly available Indian alternatives include:
- Adriamycin RTU – Pfizer
- Lyphidox – Alkem Laboratories
- Oncodria – Sun Pharma
- Zubidox – RPG Life Sciences
- Doxorubicin – Dr. Reddy’s
- Rubinat
- Oncodox
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⚠️ Disclaimer
This medicine should only be used under the supervision of a qualified oncologist. Dosage and treatment depend on individual medical conditions.
