VISVIN Decitabine 30 mg Injection
VISVIN Decitabine 30 mg Injection is an anticancer chemotherapy medicine used in the treatment of blood cancers such as myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). It contains Decitabine, which belongs to a class of medicines known as hypomethylating agents.
VISVIN Decitabine works by modifying abnormal DNA methylation in cancer cells, helping restore normal bone marrow function, improving blood cell production, and slowing disease progression. It is widely used in patients who are not suitable for intensive chemotherapy.
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Composition and Content
- Active Ingredient: Decitabine
- Strength: 30 mg
- Dosage Form: Lyophilized powder for injection
- Route: Intravenous (IV) infusion
How VISVIN Works
VISVIN Decitabine works by:
- Inhibiting DNA methyltransferase enzymes
- Reactivating tumor suppressor genes
- Slowing abnormal cancer cell growth
- Supporting healthy bone marrow function
Uses & Indications
VISVIN Decitabine 30 mg Injection is indicated for:
- Myelodysplastic Syndromes (MDS)
- Acute Myeloid Leukemia (AML)
- Pre-leukemic blood conditions
- Elderly or high-risk cancer patients
Dosage and Administration
- Administered only under medical supervision
- Given as IV infusion in hospital settings
- Dosage depends on patient condition and body surface area
- Usually given in cycles (3-day or 5-day regimens every 4 weeks)
How to Use
- Reconstitute with sterile solution before use
- Administer via IV infusion by healthcare professionals
- Regular monitoring of blood counts required
- Follow oncologist’s prescribed schedule strictly
Advantages of VISVIN Decitabine
- Effective for MDS and AML treatment
- Suitable for elderly or frail patients
- Improves blood cell production
- Delays disease progression
- Better tolerated than intensive chemotherapy
Storage Conditions
- Store below 25°C
- Protect from light and moisture
- Do not freeze
- Use immediately after reconstitution
Possible Side Effects
- Low blood counts (anemia, neutropenia, thrombocytopenia)
- Fever or infection risk
- Fatigue
- Nausea and vomiting
- Injection site reactions
Medical supervision is essential during treatment.
Alternative Indian Brands / Options
Some available alternatives include:
- Dacogen (reference innovator brand)
- Generic Decitabine injections manufactured by Indian pharmaceutical companies
Availability may vary depending on supplier and hospital procurement.
Treatments Supported by Decitabine
- Epigenetic therapy for blood cancers
- Myelodysplastic syndrome management
- Acute myeloid leukemia treatment
- Combination chemotherapy regimens
- Supportive oncology care
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