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Palnat Palbociclib 75 mg Capsules

Palnat Palbociclib 75 mg Capsules is an advanced anti-cancer medication used primarily in the treatment of certain types of breast cancer. It belongs to a class of targeted therapy drugs known as CDK4/6 inhibitors, which work by slowing or stopping the growth of cancer cells. This medicine is often prescribed in combination with hormone therapy to improve treatment outcomes in patients with hormone receptor-positive (HR+), HER2-negative advanced or metastatic breast cancer.

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Composition and Content

Active Ingredient: Palbociclib – 75 mg
Drug Class: Cyclin-dependent kinase (CDK) 4/6 inhibitor
Form: Oral capsules

Palbociclib works by inhibiting CDK4 and CDK6 proteins, which are responsible for cell division. By blocking these proteins, it prevents cancer cells from multiplying.

How to Use

Take the capsule orally with food, preferably at the same time each day.
Swallow the capsule whole; do not crush, chew, or open it.
Follow the exact schedule prescribed by your oncologist.
Usually taken in cycles (e.g., 21 days on treatment followed by 7 days off).

Dosage

Standard starting dose: 125 mg once daily (dose may be reduced to 100 mg or 75 mg based on tolerance).
Your doctor may prescribe 75 mg as a reduced dose due to side effects or patient-specific conditions.
Dose adjustments depend on blood counts and side effects.

Uses

Palnat Palbociclib is used for:

Hormone receptor-positive (HR+) breast cancer
HER2-negative advanced or metastatic breast cancer
Used in combination with:
- Aromatase inhibitors (e.g., letrozole)
- Fulvestrant

Treatments (Combination Therapy)

First-line therapy with hormone therapy
Second-line treatment after progression of cancer
Often part of long-term cancer management plans

Advantages

Targeted therapy with better precision than traditional chemotherapy
Helps delay disease progression
Improves progression-free survival
Oral administration (convenient compared to injections)
Can be combined with hormonal therapy for enhanced effectiveness

Storage Conditions

Store at room temperature (20°C to 25°C)
Keep away from moisture and direct sunlight
Store in original packaging
Keep out of reach of children

Alternative Indian Brands of Palbociclib

Some commonly available alternatives include:

Palbace 75 mg Capsules
Palbonix 75 mg Capsules
Palbocent 75 mg Capsules
Palbociclib by Natco Pharma
Palbocip 75 mg Capsules

(Always consult a doctor before switching brands.)