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Olvorin Leucovorin 100 mg Injection


Olvorin Leucovorin 100 mg Injection contains Leucovorin Calcium (Folinic Acid), a reduced form of folic acid. It is widely used in cancer treatment protocols to either enhance the effectiveness of chemotherapy drugs or reduce their toxic side effects.


Leucovorin plays a critical role in protecting healthy cells while allowing chemotherapy agents to target cancer cells effectively. It is commonly used alongside drugs like methotrexate and 5-fluorouracil.



Composition & Content

  • Active Ingredient: Leucovorin Calcium (Folinic Acid)
  • Strength: 100 mg per vial
  • Form: Sterile injection (for IV/IM administration)
  • Category: Antidote / Chemotherapy Adjuvant

Leucovorin is not a chemotherapy drug itself but acts as a biochemical modulator in cancer therapy.



How to Use

  • Administered by a qualified healthcare professional
  • Given via:
    • Intravenous (IV) injection or infusion
    • Intramuscular (IM) injection
  • Usage depends on:
    • Type of cancer
    • Chemotherapy regimen
    • Patient condition

Important: Never self-administer. Always use under strict medical supervision.



Dosage


Dosage varies depending on indication:

1. Methotrexate Rescue Therapy

  • Typically given 24 hours after methotrexate
  • Dose depends on methotrexate levels in blood

2. Colorectal Cancer (with 5-FU)

  • 20–500 mg/m² depending on treatment protocol

3. Folate Deficiency

  • As prescribed by a doctor

Note: Dosage must be individualized by an oncologist.



Uses & Treatments


Olvorin Leucovorin Injection is used in:

  • Colorectal cancer treatment
  • Gastric and pancreatic cancers (in combination therapy)
  • Methotrexate toxicity management
  • Folate deficiency anemia
  • Enhancing chemotherapy effectiveness (5-FU regimens)

Advantages

  • Reduces toxicity of methotrexate
  • Enhances effectiveness of chemotherapy drugs
  • Protects healthy cells from damage
  • Improves patient tolerance to cancer treatment
  • Well-established and widely used in oncology protocols

Storage Conditions

  • Store at 2°C to 8°C (refrigerated)
  • Protect from light and moisture
  • Do not freeze
  • Keep out of reach of children
  • Use immediately after reconstitution (if applicable)

Alternative Indian Brands of Leucovorin Injection


Some commonly available Indian alternatives include:

  • Leucovorin Calcium Injection – Fresenius Kabi
  • Calcium Folinate Injection – Neon Laboratories
  • Folinate Injection – Samarth Life Sciences
  • Leucorin Injection – Zydus Cadila
  • Folinic Acid Injection – Intas Pharmaceuticals

(Availability may vary; consult a medical supplier or exporter.)



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Conclusion


Olvorin Leucovorin 100 mg Injection is an essential supportive medication in modern cancer therapy, helping both to enhance chemotherapy effectiveness and minimize toxicity. With proper medical supervision, it significantly improves treatment outcomes and patient safety.


For reliable global access to this medicine, GlobMedIndia ensures quality, affordability, and timely delivery worldwide.



Contact Details


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📧 Email: info@globmedindia.com
📞 Phone: +91 9730316395
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 2026-04-01T07:38:36

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