Flurasted 5 Fluorouracil 1 gm Injection
Flurasted 5 Fluorouracil 1 gm Injection is a chemotherapy medicine containing Fluorouracil, used widely in the treatment of various cancers. It belongs to the antimetabolite class of anti-cancer drugs and works by blocking DNA and RNA synthesis in rapidly dividing cancer cells, which slows or stops tumor growth. It is commonly used in oncology protocols either alone or in combination with other chemotherapy agents, under strict medical supervision.
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Composition and Content
- Active Ingredient: Fluorouracil (5-FU) 1 gm
- Dosage Form: Injectable solution for IV use
- Drug Class: Antimetabolite (pyrimidine analog)
- Route of Administration: Intravenous (IV)
Mechanism of Action (Explanation)
Fluorouracil works by inhibiting thymidylate synthase, an enzyme required for DNA synthesis. This prevents cancer cells from multiplying and leads to cell death, especially in rapidly growing tumors.
Uses and Indications
Flurasted 5 Fluorouracil Injection is used in the treatment of:
- Colorectal cancer
- Breast cancer
- Gastric (stomach) cancer
- Pancreatic cancer
- Head and neck cancers
It is commonly used as part of combination chemotherapy regimens.
Dosage and Administration
- Administered only by qualified healthcare professionals
- Dose depends on:
- Body surface area (BSA)
- Type and stage of cancer
- Patient’s condition
- Given as IV bolus or continuous infusion in cycles
Important: Not for self-administration.
How to Use
- Administer via intravenous route under medical supervision.
- May be given as injection or infusion depending on protocol.
- Regular monitoring of blood counts is required.
Advantages
- Well-established chemotherapy drug
- Effective against multiple solid tumors
- Widely used in combination therapy
- Cost-effective cancer treatment option
Possible Side Effects
- Nausea and vomiting
- Diarrhea
- Mouth ulcers
- Bone marrow suppression
- Skin sensitivity
Immediate medical attention is required for severe reactions.
Storage Conditions
- Store below 25°C
- Protect from light
- Do not freeze
- Keep out of reach of children
Alternative Indian Brands for Fluorouracil Injection
- 5-FU Injection IP (various manufacturers)
- Fluorouracil Injection generic versions
- Adrucil
(Availability may vary depending on manufacturer and region.)
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