Eleftha Trastuzumab Emtansine 375 mg Injection
Eleftha Trastuzumab Emtansine 375 mg Injection is an advanced targeted anti-cancer medication used in the treatment of HER2-positive breast cancer. It combines the monoclonal antibody Trastuzumab Emtansine with a cytotoxic agent (DM1), allowing direct delivery of chemotherapy to cancer cells while minimizing damage to healthy tissues.
This innovative antibody-drug conjugate (ADC) works by specifically targeting HER2 receptors present on cancer cells, binding to them, and releasing the chemotherapy agent inside the tumor cell. This targeted approach enhances treatment effectiveness and reduces systemic side effects compared to traditional chemotherapy.
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Composition and Content
- Active Ingredient: Trastuzumab Emtansine
- Strength: 375 mg per vial
- Form: Lyophilized powder for intravenous infusion
- Class: Antibody-Drug Conjugate (ADC)
Uses of Eleftha Trastuzumab Emtansine Injection
- Treatment of HER2-positive metastatic breast cancer
- Used in patients previously treated with trastuzumab and taxane-based chemotherapy
- Adjuvant therapy for residual invasive breast cancer after neoadjuvant treatment
How It Works
Eleftha binds to HER2 receptors on cancer cells and delivers a potent cytotoxic agent directly inside the cell. This:
- Stops cancer cell growth
- Induces apoptosis (cell death)
- Minimizes damage to normal cells
Advantages
- ✔ Targeted therapy with higher precision
- ✔ Reduced systemic toxicity compared to conventional chemotherapy
- ✔ Improved progression-free survival rates
- ✔ Convenient dosing schedule (usually every 3 weeks)
- ✔ Effective in resistant HER2-positive breast cancer cases
Dosage & Administration
- Administered via intravenous infusion
- Typical dose: 3.6 mg/kg body weight every 3 weeks
- Must be given under supervision of an oncologist
- Dose adjustments may be required based on patient response and side effects
Storage Conditions
- Store at 2°C to 8°C (refrigerated)
- Do not freeze
- Protect from light
- Keep in original packaging until use
- Use reconstituted solution immediately or as directed
Alternate Indian Brands for Trastuzumab Emtansine
- Kadcyla (by Roche)
- Vivitra (Trastuzumab Emtansine variants available in India)
- Other biosimilar HER2-targeted therapies may be prescribed based on availability
Buy Eleftha Trastuzumab Emtansine 375 mg Injection Online – GlobMedIndia
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Conclusion
Eleftha Trastuzumab Emtansine 375 mg Injection is a highly effective targeted therapy for HER2-positive breast cancer, offering improved outcomes with fewer side effects. With GlobMedIndia, patients worldwide can access this life-saving medication with fast, reliable, and secure delivery.
