Biovorin Leucovorin Calcium 50 mg Tablets
Introduction
Biovorin Leucovorin Calcium Tablets contain Leucovorin Calcium, a chemically reduced form of folic acid (also known as folinic acid). Unlike regular folic acid, it does not require enzymatic conversion and is readily usable by the body.
It is widely used in oncology to:
- Enhance the effectiveness of chemotherapy (especially with Fluorouracil)
- Reduce the toxic effects of high-dose Methotrexate therapy (a process known as leucovorin rescue)
Composition and Content
- Active Ingredient: Leucovorin Calcium
- Strength: 50 mg per tablet
- Form: Oral tablets
Leucovorin bypasses the metabolic block caused by folic acid antagonists and helps protect healthy cells.
How to Use
- Take the tablet orally with water.
- Can be taken with or without food.
- Always follow the oncologist’s prescription strictly.
- Timing is critical when used with chemotherapy—especially after Methotrexate.
Dosage
Dosage depends on the treatment purpose:
- Leucovorin Rescue (after Methotrexate):
- Typically 10–25 mg every 6 hours (dose varies based on Methotrexate levels)
- With Fluorouracil (Cancer Therapy):
- 20–500 mg/m² depending on regimen
- Folate Deficiency:
- Lower doses as prescribed
⚠️ Important: Never self-medicate; dosage must be decided by a healthcare professional.
Uses & Treatments
Biovorin is used in:
- Colorectal cancer treatment (in combination with Fluorouracil)
- Leucovorin rescue therapy after Methotrexate overdose
- Treatment of folate deficiency
- Adjunct therapy in chemotherapy protocols
Advantages
- Protects normal cells from chemotherapy toxicity
- Enhances chemotherapy effectiveness
- Rapid action (does not require metabolic activation)
- Reduces side effects like bone marrow suppression
Storage Conditions
- Store below 25°C
- Keep in a dry place away from sunlight
- Keep out of reach of children
- Do not use expired tablets
Alternative Indian Brands for Leucovorin Calcium Tablets (15 mg / 50 mg)
Here are commonly available Indian alternatives:
- Folinine Tablets
- Leucorin Tablets
- Rescuvolin Tablets
- Leucovorin Calcium Tablets by Cipla
- Leucovorin Calcium by Zydus Cadila
- Folinic Acid Tablets by Intas Pharmaceuticals
(Availability may vary; always verify with a licensed exporter or supplier.)
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Conclusion
Biovorin Leucovorin Calcium 50 mg Tablets play a crucial role in modern oncology by both enhancing chemotherapy effectiveness and reducing toxicity. Whether used for leucovorin rescue or combination therapy, it is an essential medication that must be administered under expert supervision. Choosing a trusted supplier like GlobMedIndia ensures quality, safety, and timely global access.
Contact Details
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- 📧 Email: info@globmedindia.com
- 📞 Phone: +91 9730316395
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