Avonza Tablet is a fixed-dose combination of three antiretroviral medicines: Lamivudine, Tenofovir Disoproxil Fumarate, and Efavirenz (400 mg). It is widely used in the treatment of HIV-1 infection as part of first-line antiretroviral therapy (ART). This combination works by inhibiting viral replication at multiple stages, helping to control the virus and improve immune function.
Uses of Avonza Tablet
- Treatment of HIV-1 infection
- Part of first-line antiretroviral therapy (ART)
- Helps reduce viral load in the blood
- Improves CD4 cell count
- Prevents progression to AIDS
Dosage & Administration
- Recommended dose: 1 tablet once daily
- Preferably taken at bedtime to reduce side effects (Efavirenz-related)
- Take on an empty stomach for better absorption
- Swallow whole with water
- Follow doctor’s prescription strictly
Treatment Benefits
- Triple-drug combination for effective HIV suppression
- Reduces viral load to undetectable levels
- Improves immune system function
- Decreases risk of opportunistic infections
- Supports long-term HIV management
Advantages of Avonza
- Lower dose Efavirenz (400 mg) reduces side effects compared to 600 mg
- Convenient once-daily single tablet regimen
- Improves patient adherence
- Cost-effective and widely recommended
- Clinically proven safety and efficacy
Storage Conditions
- Store at 20°C–25°C (room temperature)
- Protect from heat, light, and moisture
- Keep in original packaging
- Keep out of reach of children
Alternative Indian Brands (Lamivudine + Tenofovir + Efavirenz)
- Viraday – Cipla Ltd.
- TLE 400 (Tenofovir + Lamivudine + Efavirenz 400 mg) – Mylan/Viatris
- Efavir-LT 400 – Hetero Healthcare
- Tenvir-EM + Efavirenz combinations – Cipla
- Trioday (similar ART combinations) – Mylan
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Conclusion
Avonza Tablet (Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg + Efavirenz 400 mg) is a highly effective and widely recommended first-line treatment for HIV infection. Its once-daily dosing and reduced Efavirenz strength improve patient compliance and tolerability while maintaining strong antiviral efficacy.
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