Regonat Regorafenib 40 mg Tablets
Regonat Regorafenib 40 mg Tablets contain Regorafenib, an oral multi-kinase inhibitor used in the treatment of advanced cancers. It works by blocking multiple protein kinases involved in tumor growth, angiogenesis (formation of new blood vessels), and cancer progression. Regonat is commonly prescribed when standard treatments have not been effective, making it a crucial option in targeted cancer therapy.
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Composition and Content
Active Ingredient: Regorafenib 40 mg
Form: Oral Tablets
Drug Class: Multi-kinase inhibitor (Targeted Therapy)
Regorafenib targets several pathways including VEGFR, PDGFR, and RAF kinases, helping to slow tumor growth and reduce blood supply to cancer cells.
How to Use
Take the tablet orally with water, preferably after a low-fat meal.
Swallow whole; do not crush or chew.
Follow the oncologist’s prescription strictly.
Treatment is usually given in cycles (e.g., 3 weeks on treatment, 1 week off).
Dosage
Standard Dose: 160 mg (4 tablets of 40 mg) once daily for 21 days, followed by 7 days off (28-day cycle).
Dose adjustments may be required based on patient tolerance and side effects.
Always consult a doctor before altering dosage.
Uses
Regonat Regorafenib is used in the treatment of:
Metastatic colorectal cancer (mCRC)
Gastrointestinal stromal tumors (GIST)
Hepatocellular carcinoma (HCC – liver cancer)
Treatments & Mechanism
Regorafenib works by:
Inhibiting tumor angiogenesis (blood vessel formation)
Blocking oncogenic kinases that promote tumor growth
Slowing cancer cell proliferation
This makes it effective in advanced-stage cancers where other therapies may fail.
Advantages
Oral administration (no hospitalization required)
Targets multiple cancer pathways
Effective in resistant or advanced cancers
Improves progression-free survival
Storage Conditions
Store at room temperature (15°C to 30°C)
Keep away from moisture and direct sunlight
Store in original packaging
Keep out of reach of children
Alternative Indian Brands for Regorafenib 40 mg
Some commonly available alternatives include:
Stivarga (Bayer)
Regonat (Natco Pharma)
Regorafenib by Cipla
Regorafenib by Dr. Reddy’s Laboratories
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