Nuparp Rucaparib 300 mg Tablet
Nuparp Rucaparib 300 mg tablet is an advanced targeted anti-cancer medication used in the treatment of certain types of ovarian, fallopian tube, and primary peritoneal cancers. It belongs to a class of drugs known as PARP (Poly ADP-Ribose Polymerase) inhibitors, which work by blocking cancer cells' ability to repair their DNA, ultimately causing their death.
Rucaparib is especially effective in patients with BRCA gene mutations and is commonly prescribed as a maintenance therapy to prevent cancer recurrence after chemotherapy.
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Composition and Content
Active Ingredient: Rucaparib
Strength: 300 mg per tablet
Form: Oral tablets
Class: PARP Inhibitor (Targeted Therapy)
How to Use
Take the tablet orally with or without food.
Swallow the tablet whole with water; do not crush or chew.
Follow the doctor’s prescription strictly.
Maintain consistent timing for better therapeutic effect.
Dosage
Typical Dose: 600 mg per day (300 mg twice daily)
Dose may vary depending on:
Patient’s condition
Response to treatment
Side effects
Never adjust dosage without consulting a healthcare professional.
Uses
Nuparp Rucaparib 300 mg is used for:
Ovarian cancer treatment
Fallopian tube cancer
Primary peritoneal cancer
Maintenance therapy after chemotherapy
Treatment of BRCA-mutated cancers
Treatments & Mechanism of Action
Rucaparib inhibits the PARP enzyme, which helps repair damaged DNA.
Cancer cells rely heavily on PARP due to defective DNA repair mechanisms.
Blocking PARP leads to accumulation of DNA damage, resulting in cancer cell death.
Particularly effective in homologous recombination deficiency (HRD) tumors.
Advantages
Targeted therapy with higher precision
Effective in BRCA-mutated cancers
Helps delay cancer progression
Oral administration (no hospital stay required)
Improves progression-free survival
Storage Conditions
Store at room temperature (20°C–25°C)
Keep away from moisture and direct sunlight
Store in original packaging
Keep out of reach of children
Alternative Indian Brands for Rucaparib
Some alternative brands available in India include:
Rucaparib Tablets by Dr. Reddy’s Laboratories
Rucapax by BDR Pharmaceuticals
Rucapar by Natco Pharma
Bracanat (Rucaparib generic versions)
(Availability may vary; consult supplier or oncologist)
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