JAKAVI (Ruxolitinib) 5 mg Tablets
Introduction
JAKAVI 5 mg Tablets contain Ruxolitinib, a targeted therapy used in the treatment of certain blood disorders and cancers. It belongs to a class of medicines known as Janus kinase (JAK) inhibitors, which work by blocking enzymes responsible for abnormal blood cell production and inflammation. JAKAVI is widely prescribed for conditions like myelofibrosis and polycythemia vera, helping improve symptoms and quality of life.
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Composition and Content
Active Ingredient: Ruxolitinib
Strength: 5 mg per tablet
Form: Oral tablets
Drug Class: Janus Kinase (JAK1/JAK2) inhibitor
How JAKAVI Works
Ruxolitinib blocks JAK1 and JAK2 enzymes involved in blood cell signaling. This action helps:
Reduce abnormal blood cell production
Decrease spleen enlargement
Control inflammation and immune response
Uses of JAKAVI 5 mg Tablets
JAKAVI is primarily used for:
Myelofibrosis (primary or secondary)
Polycythemia Vera (in patients resistant to hydroxyurea)
Graft-versus-host disease (GVHD)
Certain inflammatory and hematologic conditions
Dosage and Administration
Dosage depends on platelet count and patient condition
Common starting dose: 5 mg twice daily (may vary)
Taken orally with or without food
Dose adjustments required based on response and side effects
Always follow doctor’s prescription strictly
How to Use
Swallow tablet whole with water
Do not crush or chew
Take at the same time daily
Regular blood tests required during treatment
Benefits and Advantages
Reduces spleen size effectively
Improves symptoms like fatigue, night sweats, and bone pain
Better disease control compared to conventional therapies
Oral administration (no injections required)
Improves overall quality of life
Storage Conditions
Store at room temperature (below 25°C)
Keep away from moisture and direct sunlight
Keep out of reach of children
Do not use expired tablets
Possible Side Effects
Anemia
Thrombocytopenia (low platelets)
Infections
Headache
Dizziness
Weight gain
Note: Seek medical attention if severe side effects occur.
Alternative Indian Brands for Ruxolitinib 5 mg
Some commonly available alternatives include:
Ruxolitib (Cipla)
Ruxonib (Hetero Healthcare)
Jaknat (Natco Pharma)
Ruxolitinib Tablets (Dr. Reddy’s Laboratories)
(Consult your doctor before switching brands.)
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