UNIBLASTIN Vinblastine 10mg/10ml Injection
Introduction
UNIBLASTIN Vinblastine 10mg/10ml Injection is a chemotherapeutic medicine primarily used to treat various types of cancer, including leukemia, lymphoma, and solid tumors. It belongs to the class of vinca alkaloids, which work by inhibiting the growth of cancer cells by stopping cell division.
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Composition and Content
Each 10ml vial of UNIBLASTIN Vinblastine Injection contains:
- Active Ingredient: Vinblastine Sulfate 10mg
- Excipients: Sterile water for injection, sodium chloride, and other pharmaceutical-grade stabilizers.
- Form: Clear, colorless to slightly yellow solution suitable for intravenous use.
How to Use
- Administered intravenously (IV) under strict medical supervision.
- The injection should be given slowly over 5–10 minutes to avoid toxicity.
- Dosage and schedule depend on the type of cancer, patient’s body surface area (BSA), and overall health condition.
- Should never be administered intrathecally as it can be fatal.
Recommended Doses
- Adults: 0.1–0.3 mg/kg per week depending on therapy protocol.
- Children: 0.05–0.2 mg/kg per week, adjusted by pediatric oncologist.
- Dose modifications may be necessary in patients with liver dysfunction.
Uses and Treatments
UNIBLASTIN Vinblastine is used for:
- Hodgkin’s and non-Hodgkin’s lymphoma
- Acute and chronic leukemia
- Testicular cancer
- Breast cancer
- Kaposi’s sarcoma
- Other solid tumors as prescribed
Advantages
- Potent anti-cancer effect by inhibiting microtubule formation in cancer cells.
- Can be combined with other chemotherapy agents for synergistic effects.
- Proven effectiveness in both adults and pediatric patients.
- Administered as a short IV infusion, minimizing hospital stay.
Storage Conditions
- Store at 2°C to 8°C (refrigerated).
- Protect from light and freezing.
- Keep vials in original packaging until use.
- Keep out of reach of children and pets.
Alternative Indian Brands
- Velban 10mg Injection – Cipla
- Vinblastine Sulfate Injection – Sun Pharma
- Vincaleuk 10mg/10ml Injection – Zydus Cadila
- Vinblastine Injection – Mylan Pharma
These alternatives offer similar composition and efficacy, allowing flexibility in treatment availability.
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