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Purchase Today online Kadcyla Trastuzumab Emtansine 160mg Injection for GlobMedIndia - The Medicine Exporter India - Nagpur, Mumbai, Delhi, Rajasthan, Kerala, Uttar Pradesh, Pune, Gujarat, Surat.

Kadcyla Trastuzumab Emtansine 160mg Injection 


Kadcyla (Trastuzumab Emtansine) 160mg Injection is a targeted anti-cancer medication used primarily for the treatment of HER2-positive metastatic breast cancer. It is a combination of a monoclonal antibody (trastuzumab) and a cytotoxic agent (emtansine), designed to deliver chemotherapy directly to HER2-positive cancer cells while minimizing exposure to healthy cells. This makes it highly effective in controlling tumor growth with fewer systemic side effects compared to traditional chemotherapy.


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Composition and Content

  • Trastuzumab – a monoclonal antibody that targets the HER2 receptor on cancer cells.
  • Emtansine (DM1) – a cytotoxic agent linked to trastuzumab for targeted chemotherapy.
  • Excipients – includes stabilizers, buffers, and other components to maintain solution integrity.
  • Dosage Form – 160 mg per vial as a sterile, lyophilized powder for intravenous infusion.

How to Use & Dosage

  • Administration: Intravenous infusion under medical supervision.
  • Recommended Dose: Typically 3.6 mg/kg body weight every 3 weeks, but dosage may be adjusted based on patient condition and tolerance.
  • Infusion Time: Usually over 30–90 minutes, depending on tolerance.
  • Precautions: Pre-medication may be required to prevent infusion-related reactions. Patients should be monitored for cardiac function and liver health.

Uses and Treatments

  • Primary use in HER2-positive metastatic breast cancer patients who previously received trastuzumab and a taxane.
  • Helps in slowing cancer progression, reducing tumor size, and improving survival rates.
  • Often used as part of a comprehensive treatment plan including surgery, radiotherapy, or other chemotherapies.

Advantages

  • Targeted therapy reduces systemic side effects.
  • Combines the efficacy of trastuzumab with the cytotoxic effect of emtansine.
  • Convenient dosing schedule (every 3 weeks).
  • Improves progression-free survival in HER2-positive breast cancer patients.

Storage Conditions

  • Store 2°C–8°C (refrigerated).
  • Protect from light.
  • Do not freeze.
  • Use immediately after reconstitution or follow recommended storage after dilution.

Alternative Indian Brands

  • T-DM1 Biocon – India-based biosimilar option.
  • Kadtraz – alternative by Indian pharmaceutical companies for trastuzumab emtansine.
  • Trastemax – another locally manufactured biosimilar.

(Availability may vary; consult your oncologist for suitability.)



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 2026-04-07T16:57:48

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