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Lorbriqua (Lorlatinib) 100 mg Tablets 

Introduction

Lorbriqua (Lorlatinib) 100 mg Tablets is a targeted anti-cancer medication used primarily in the treatment of advanced lung cancer. It belongs to a class of drugs known as ALK (Anaplastic Lymphoma Kinase) inhibitors, which are designed to block specific proteins responsible for cancer growth.

This medicine is widely prescribed for patients with ALK-positive metastatic non-small cell lung cancer (NSCLC), especially those who have developed resistance to earlier treatments.

Composition and Content

• Active Ingredient: Lorlatinib 100 mg
• Drug Class: Tyrosine Kinase Inhibitor (TKI)
• Form: Oral Tablets

Lorlatinib works by targeting abnormal ALK and ROS1 proteins that promote tumor growth, effectively slowing or stopping cancer progression.

How to Use

• Take the tablet orally with or without food.
• Swallow whole with water; do not crush or chew.
• Take at the same time every day for best results.
• Follow your oncologist’s instructions strictly.

Dosage

• Standard Dose: 100 mg once daily
• Dose adjustments may be required based on:
  • Side effects
  • Liver function
  • Drug interactions

⚠️ Always consult a healthcare professional before changing dosage.

Uses

Lorbriqua (Lorlatinib) is used for:

• Treatment of ALK-positive non-small cell lung cancer (NSCLC)
• Patients who:
  • Have progressed after prior ALK inhibitor therapy
  • Show resistance to earlier treatments

Treatment Benefits

• Targets cancer at a molecular level
• Effective in brain metastases (crosses blood-brain barrier)
• Suitable for patients with treatment-resistant lung cancer
• Improves progression-free survival

Advantages

• Highly specific targeted therapy
• Oral administration (no hospitalization needed)
• Effective against advanced-stage cancers
• Better management of tumor spread to brain

Possible Side Effects

• Increased cholesterol or triglycerides
• Swelling (edema)
• Mood changes or cognitive effects
• Fatigue
• Weight gain

⚠️ Regular monitoring and blood tests are recommended.

Storage Conditions

• Store at room temperature (20°C to 25°C)
• Keep away from moisture and direct sunlight
• Keep out of reach of children

Alternative Indian Brands of Lorlatinib

Some alternative brands available in India include:

• Lorlatinib Tablets by Natco Pharma
• Lorlatinib by Dr. Reddy’s Laboratories
• Lorlatinib by Hetero Healthcare
• Lorlatinib by Zydus Cadila

These brands offer cost-effective options with similar efficacy.

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Conclusion

Lorbriqua (Lorlatinib) 100 mg Tablets is a breakthrough therapy for patients suffering from ALK-positive lung cancer, especially in advanced stages. With its targeted mechanism and effectiveness against resistant cancer cells, it significantly improves patient outcomes.

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