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Reditux Rituximab 100 mg Injection

Introduction

Reditux Rituximab 100 mg Injection is a targeted anti-cancer medication used in the treatment of various blood cancers and autoimmune disorders. It contains rituximab, a monoclonal antibody that specifically targets CD20 proteins found on B-cells, helping the immune system destroy these abnormal or cancerous cells.

This injection is widely used in oncology and immunology due to its effectiveness in treating conditions like non-Hodgkin lymphoma, chronic lymphocytic leukemia, and certain autoimmune diseases such as rheumatoid arthritis.

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Composition and Content

Active Ingredient: Rituximab
Strength: 100 mg per vial
Formulation: Sterile liquid for intravenous infusion
Category: Monoclonal Antibody (Anti-CD20)

How to Use

Administered intravenously (IV infusion) under strict medical supervision
Usually given in a hospital or oncology clinic
Pre-medications (like antihistamines, paracetamol, corticosteroids) may be given to reduce infusion reactions
Infusion time may vary from 1.5 to 6 hours, depending on patient tolerance

Dosage

Dosage depends on the patient’s condition, weight, and treatment protocol:

Non-Hodgkin Lymphoma:
375 mg/m² once weekly or as per chemotherapy cycle
Chronic Lymphocytic Leukemia (CLL):
Given in combination with chemotherapy
Rheumatoid Arthritis:
Two doses of 1000 mg given 2 weeks apart

⚠️ Always follow the oncologist’s prescription strictly.

Uses

Reditux Rituximab 100 mg Injection is used in the treatment of:

Non-Hodgkin Lymphoma
Chronic Lymphocytic Leukemia
Rheumatoid Arthritis
Granulomatosis with Polyangiitis
Microscopic Polyangiitis

Treatments & Mechanism

Rituximab works by targeting the CD20 antigen on B-lymphocytes. It destroys these cells through:

Immune-mediated cytotoxicity
Direct apoptosis (cell death)
Complement activation

This reduces abnormal B-cells responsible for cancer or autoimmune damage.

Advantages

Targeted therapy with high precision
Effective in relapsed or resistant cancers
Reduces disease progression
Can be combined with chemotherapy
Improves survival rates in many patients

Storage Conditions

Store at 2°C to 8°C (refrigerated)
Do not freeze
Keep away from direct sunlight
Store in original packaging
Keep out of reach of children

Alternative Indian Brands of Rituximab

Here are some commonly available alternatives in India:

MabThera
Ristova
Rituxirel
Reditux
Maball