Stelera Ustekinumab 90 mg Injection
Introduction
Stelera Ustekinumab 90 mg Injection is a biologic medication used primarily for the treatment of autoimmune conditions such as moderate to severe plaque psoriasis, psoriatic arthritis, and certain inflammatory bowel diseases. It works by targeting specific proteins (interleukin-12 and interleukin-23) in the immune system to reduce inflammation and abnormal immune responses. This targeted mechanism helps in controlling symptoms effectively and improving patients’ quality of life.
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Composition and Content
- Active Ingredient: Ustekinumab 90 mg (per prefilled syringe)
- Formulation: Sterile, clear solution for subcutaneous injection
- Excipients: L-histidine, L-histidine hydrochloride monohydrate, sucrose, polysorbate 80, water for injection
How to Use
- Route: Subcutaneous injection
- Administration: Administered by a healthcare professional. Common injection sites include the abdomen, thigh, or upper arm. Rotate injection sites with each dose to reduce irritation.
- Preparation: Allow the syringe to reach room temperature before administration. Do not shake the vial vigorously.
Recommended Doses
- Induction Dose: Initial dose of 45 mg or 90 mg depending on patient weight (≤100 kg: 45 mg, >100 kg: 90 mg).
- Maintenance Dose: Follow-up injections are given every 12 weeks.
- Adjustment: Dose adjustments may be considered based on clinical response or adverse effects.
Uses and Treatments
- Psoriasis: Reduces redness, scaling, and plaque thickness in moderate to severe cases.
- Psoriatic Arthritis: Improves joint pain, swelling, and stiffness.
- Crohn’s Disease & Ulcerative Colitis: Helps control inflammation and flare-ups in some patients.
Advantages
- Targeted treatment reduces systemic side effects compared to traditional immunosuppressants.
- Long dosing interval (every 12 weeks) improves patient compliance.
- Clinically proven efficacy in multiple autoimmune disorders.
- Can be combined with other therapies under medical supervision for enhanced outcomes.
Storage Conditions
- Store at 2°C to 8°C (36°F to 46°F) in a refrigerator.
- Protect from light and do not freeze.
- Keep out of reach of children.
- Use within a specific period after opening or removal from refrigeration as per package instructions.
Alternative Indian Brands for Stelera Ustekinumab 90 mg Injection
- Ustekinab 90 mg – Glenmark Pharmaceuticals, India
- Ustekimab 90 mg – Natco Pharma, India
- Stelkinab 90 mg – Hetero Healthcare, India
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