Elaxim Recombinant Tissue Plasminogen Activator 40mg Injection
Elaxim Recombinant Tissue Plasminogen Activator (rtPA) 40mg Injection is a thrombolytic (clot-busting) medication used in emergency medical conditions to dissolve dangerous blood clots. It contains Alteplase, a bioengineered enzyme that helps restore normal blood flow by breaking down fibrin clots in blood vessels.
This injection is commonly used in life-threatening conditions such as Acute Ischemic Stroke, Myocardial Infarction, and Pulmonary Embolism, where rapid treatment is critical to prevent permanent damage or death.
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Composition and Content
- Active Ingredient: Alteplase (Recombinant Tissue Plasminogen Activator)
- Strength: 40 mg per vial
- Form: Lyophilized powder for injection
- Class: Thrombolytic / Fibrinolytic agent
How to Use
- Administered intravenously (IV) under strict medical supervision.
- Usually given in a hospital emergency setting by trained healthcare professionals.
- Requires reconstitution with sterile water before administration.
- Continuous monitoring of vital signs and clot resolution is essential during treatment.
Dosage
Dosage varies depending on the condition being treated:
- Acute Ischemic Stroke: Weight-based dosing within a specific time window (usually within 3–4.5 hours of symptom onset)
- Heart Attack (MI): Accelerated infusion protocol
- Pulmonary Embolism: Infusion over a specified period
⚠️ Always follow physician-prescribed dosing. Self-administration is strictly prohibited.
Uses and Treatments
Elaxim 40mg Injection is used in the treatment of:
- Acute ischemic stroke
- Myocardial infarction (heart attack)
- Pulmonary embolism
- Blocked central venous catheters
It works by converting plasminogen to plasmin, which dissolves fibrin clots and restores blood circulation.
Advantages
- Rapid clot dissolution in emergency situations
- Helps reduce mortality and disability
- Restores blood flow quickly to vital organs
- Widely used and clinically proven therapy
Storage Conditions
- Store at 2°C to 8°C (refrigerated)
- Protect from light and moisture
- Do not freeze
- Use immediately after reconstitution
Alternative Indian Brands
Some commonly available Indian alternatives containing Alteplase include:
- Actilyse
- Alteplase Injection
- Alteplase for Injection
(Availability may vary depending on hospital supply and region.)
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