Ujvira Trastuzumab Emtansine 160 mg Injection
Ujvira Trastuzumab Emtansine 160 mg Injection is an advanced targeted anti-cancer medication used primarily for the treatment of HER2-positive breast cancer. It is a combination drug (antibody-drug conjugate) that delivers chemotherapy directly to cancer cells, improving effectiveness while reducing damage to healthy tissues.
This injection contains Trastuzumab emtansine, which combines a monoclonal antibody (trastuzumab) with a cytotoxic agent (DM1), specifically targeting HER2 receptors on cancer cells.
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Composition and Content
- Active Ingredient: Trastuzumab Emtansine
- Strength: 160 mg per vial
- Form: Lyophilized powder for injection
- Class: Antibody-Drug Conjugate (ADC)
- Mechanism:
- Trastuzumab binds to HER2-positive cancer cells
- Emtansine (DM1) enters the cells and destroys them from within
How to Use
- Administered intravenously (IV infusion) under medical supervision
- Given in a hospital or oncology clinic
- Reconstituted and diluted before administration
- Infusion duration typically 30–90 minutes
⚠️ Should only be given by trained healthcare professionals.
Dosage
- Recommended Dose: 3.6 mg/kg body weight
- Frequency: Once every 3 weeks (21-day cycle)
- Duration depends on:
- Patient response
- Disease progression
- Tolerance to treatment
Uses
Ujvira Trastuzumab Emtansine is used for:
- HER2-positive metastatic breast cancer
- Breast cancer patients previously treated with trastuzumab and chemotherapy
- Adjuvant treatment for residual invasive disease
Treatments & Therapeutic Benefits
- Targeted therapy for HER2-positive cancers
- Post-surgery or advanced-stage treatment
- Improves survival rates in resistant breast cancer cases
- Reduces tumor growth and spread
Advantages
- ✔ Targeted delivery reduces harm to healthy cells
- ✔ Higher efficacy compared to traditional chemotherapy
- ✔ Fewer systemic side effects
- ✔ Improves progression-free survival
- ✔ Convenient 3-week dosing schedule
Storage Conditions
- Store in a refrigerator at 2°C to 8°C
- Do not freeze
- Protect from light
- Use immediately after reconstitution (as per medical guidelines)
- Keep out of reach of children
Alternative Indian Brands
Some alternative brands of Trastuzumab Emtansine available in India include:
- Kadcyla (by Roche) – widely used original brand
- Hertkad (biosimilar, availability may vary)
- Other biosimilars depending on supplier and regulatory approvals
👉 Always consult an oncologist before switching brands.
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