Tagrisso Osimertinib 80 mg Tablets
Tagrisso (Osimertinib 80 mg Tablets) is a targeted anti-cancer medication used primarily in the treatment of non-small cell lung cancer (NSCLC) that has specific genetic mutations known as EGFR (epidermal growth factor receptor) mutations. It belongs to a class of drugs called tyrosine kinase inhibitors (TKIs), which work by blocking signals that cause cancer cells to grow and divide.
Osimertinib is considered a third-generation EGFR inhibitor, specifically designed to target both common EGFR mutations and the resistant T790M mutation, making it highly effective in patients who have developed resistance to earlier therapies.
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Composition and Content
- Active Ingredient: Osimertinib Mesylate
- Strength: Equivalent to Osimertinib 80 mg
- Form: Oral Tablets
- Packaging: Typically available in strips or bottles (varies by manufacturer)
How to Use
- Take the tablet once daily, with or without food.
- Swallow whole with water; do not crush or chew.
- Take at the same time every day for best results.
- If you miss a dose, skip it and continue with the next scheduled dose.
Dosage
- Standard Dose: 80 mg once daily
- Dosage adjustments may be made based on:
- Patient tolerance
- Side effects
- Doctor’s recommendation
⚠️ Always follow your oncologist’s prescribed dosage.
Uses
Tagrisso (Osimertinib) is used in the treatment of:
- EGFR mutation-positive non-small cell lung cancer (NSCLC)
- Metastatic lung cancer
- T790M mutation-positive NSCLC (after progression on earlier EGFR therapies)
- Adjuvant treatment after tumor removal surgery in early-stage NSCLC
Treatments & Mechanism of Action
Osimertinib works by:
- Blocking EGFR protein activity, which is responsible for cancer cell growth
- Targeting resistant cancer mutations (T790M)
- Slowing or stopping tumor progression
- Helping shrink tumors and prevent spread to other organs
Advantages
- Highly effective for EGFR-mutated lung cancer
- Works against resistant mutations (T790M)
- Better brain penetration, useful in treating brain metastases
- Oral therapy, convenient compared to chemotherapy
- Generally better tolerated than traditional chemotherapy
Storage Conditions
- Store at room temperature (20°C–25°C)
- Keep away from moisture and direct sunlight
- Keep out of reach of children
- Do not use expired medication
Recommended Alternative Indian Brands
Affordable Indian alternatives of Osimertinib 80 mg include:
- Osimert (Osimertinib 80 mg) – by Everest Pharma
- Osicent (Osimertinib 80 mg) – by Incepta Pharmaceuticals
- Tagrix (Osimertinib 80 mg) – by Beacon Pharmaceuticals
- Osimtinib (generic versions) – various Indian manufacturers
💡 These alternatives offer cost-effective treatment options with similar efficacy (consult doctor before switching).
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