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Pazinib Pazopanib 400 mg Tablets

Pazinib Pazopanib 400 mg Tablets is an anti-cancer medication used primarily in the treatment of advanced kidney cancer (renal cell carcinoma) and certain types of soft tissue sarcoma. It belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs), which work by blocking specific proteins responsible for tumor growth and blood vessel formation, thereby slowing or stopping the spread of cancer.

Pazopanib helps in targeting cancer cells more precisely compared to traditional chemotherapy, making it an effective option in targeted cancer therapy.

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Composition and Content

Active Ingredient: Pazopanib Hydrochloride
Strength: Equivalent to Pazopanib 400 mg per tablet
Form: Oral tablets
Class: Tyrosine Kinase Inhibitor (TKI)

How to Use

Take the tablet orally with water, preferably on an empty stomach (at least 1 hour before or 2 hours after food).
Swallow whole; do not crush or chew.
Follow your oncologist’s instructions strictly.
Take the medicine at the same time daily for best results.

Dosage

The usual recommended dose is 800 mg once daily (two 400 mg tablets), depending on the patient’s condition.
Dose adjustments may be required based on:
- Liver function
- Side effects
- Overall health condition

Note: Always follow the prescribed dosage by your doctor.

Uses

Pazinib Pazopanib 400 mg Tablets are used for:

Advanced Renal Cell Carcinoma (Kidney Cancer)
Soft Tissue Sarcoma (STS)
In cases where cancer has spread or cannot be surgically removed

Treatments & Mechanism

Pazopanib works by:

Inhibiting VEGF receptors (vascular endothelial growth factor)
Blocking blood supply to tumors (anti-angiogenesis)
Preventing cancer cell growth and division

This targeted approach reduces damage to healthy cells compared to traditional chemotherapy.

Advantages

Targeted therapy with fewer systemic side effects
Effective in advanced-stage cancers
Oral administration (no hospitalization required)
Helps slow disease progression
Improves quality of life in many patients

Storage Conditions

Store at room temperature (20°C–25°C)
Keep away from moisture and direct sunlight
Keep out of reach of children
Do not use expired medication

Alternative Indian Brands for Pazopanib 400 mg

Some commonly available Indian alternatives include:

Votrient 400 mg (by Novartis / GSK)
Pazolong 400 mg
Pazonat 400 mg
Pazocent 400 mg
Pazokast 400 mg

Availability may vary; consult your supplier or oncologist for the best option.