Palnat Palbociclib 100 mg Capsules
Palnat Palbociclib 100 mg Capsules is an advanced targeted anti-cancer medication used primarily in the treatment of hormone receptor-positive (HR+), HER2-negative breast cancer. It belongs to a class of drugs known as CDK4/6 inhibitors, which work by slowing down or stopping the growth of cancer cells by blocking proteins responsible for cell division.
Palbociclib is commonly prescribed in combination with hormonal therapies such as aromatase inhibitors or fulvestrant, improving treatment outcomes and delaying disease progression in patients with advanced or metastatic breast cancer.
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Composition and Content
- Active Ingredient: Palbociclib
- Strength: 100 mg per capsule
- Drug Class: Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor
- Form: Oral Capsules
How to Use
- Take the capsule orally with food, at the same time each day.
- Swallow whole with water; do not crush or chew.
- Usually taken in combination with hormone therapy (as prescribed by a doctor).
- Follow the treatment cycle strictly (commonly 21 days ON, 7 days OFF).
Dosage
- Standard starting dose: 125 mg once daily (may be reduced to 100 mg based on tolerance).
- Palnat 100 mg is often used as a dose-adjusted regimen.
- Treatment cycles are typically 28 days (21 days medication + 7 days break).
- Dosage adjustments depend on:
- Blood counts
- Side effects
- Patient response
⚠️ Always follow your oncologist’s prescription.
Uses
- Treatment of HR-positive, HER2-negative advanced or metastatic breast cancer
- Used in combination with:
- Aromatase inhibitors (e.g., letrozole)
- Fulvestrant (for disease progression cases)
Treatments & Mechanism of Action
Palbociclib works by:
- Inhibiting CDK4 and CDK6 enzymes
- Preventing cancer cells from progressing from the G1 phase to S phase in the cell cycle
- Slowing tumor growth and improving survival rates when combined with hormonal therapy
Advantages
- Targeted therapy with higher specificity for cancer cells
- Helps delay disease progression
- Improves progression-free survival
- Oral administration (convenient compared to IV therapies)
- Well-tolerated with manageable side effects
Storage Conditions
- Store at room temperature (20°C to 25°C)
- Keep in a dry place away from moisture and sunlight
- Keep out of reach of children
- Do not use expired medication
Alternative Indian Brands for Palbociclib 100 mg
Some widely available alternatives include:
- Palbace 100 mg Capsules
- Palbonix 100 mg Capsules
- Palbocent 100 mg Capsules
- Palbocip 100 mg Capsules
- Palboxen 100 mg Capsules
(Consult your doctor before switching brands.)
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