DOXORUBA (Doxorubicin 10mg Injection)
Introduction
DOXORUBA Doxorubicin 10mg Injection is a powerful chemotherapy medicine used to treat various types of cancers. It belongs to the class of anthracycline anti-cancer drugs, known for their effectiveness in stopping cancer cell growth and spreading.
Doxorubicin is widely used in oncology and is considered a core drug in many chemotherapy regimens due to its broad-spectrum anti-tumor activity.
Composition & Content
- Active Ingredient: Doxorubicin Hydrochloride
- Strength: 10 mg
- Form: Injection (usually 2 mg/mL solution)
- Class: Anthracycline antibiotic (Anti-cancer)
How it Works (Mechanism)
Doxorubicin works by:
- Binding to DNA (intercalation)
- Inhibiting topoisomerase II enzyme
- Generating free radicals that damage cancer cells
This leads to DNA damage and cancer cell death
Uses of DOXORUBA Injection
DOXORUBA is used to treat multiple cancers such as:
- Breast cancer
- Lung cancer
- Leukemia (AML, ALL)
- Lymphomas (Hodgkin & Non-Hodgkin)
- Ovarian cancer
- Bladder cancer
- Soft tissue sarcoma
- Thyroid & stomach cancers
How to Use
- Administered intravenously (IV) by a trained oncologist
- Given in hospital or clinical setting
- Infusion duration: 3–20 minutes depending on protocol
- Not for self-administration
Dosage
-
Dose depends on:
- Patient weight/body surface area (BSA)
- Type of cancer
- Combination therapy
Common Dosage:
- 40–75 mg/m² IV every 21–28 days
- Maximum cumulative dose: ~550 mg/m² (to prevent heart toxicity)
Treatments & Indications
DOXORUBA is used in:
- Chemotherapy regimens (e.g., AC, CHOP)
- Adjuvant therapy (after surgery)
- Palliative cancer treatment
- Combination cancer therapy
Advantages
- Highly effective against multiple cancers
- Proven long-term survival benefits
- Works in combination therapies
- Rapid action on cancer cells
- Widely accepted global chemotherapy drug
Storage Conditions
- Store at 2°C to 8°C (refrigerated)
- Protect from light
- Do not freeze
- Keep in original packaging
- Handle as hazardous drug
Alternative Indian Brands of Doxorubicin Injection
Some commonly available Indian alternatives include:
- Adriamycin Injection
- Doxorubicin (Cipla)
- Doxorubicin (Fresenius Kabi)
- Doxorubicin (Intas Pharmaceuticals)
- Doxorubicin (Zydus Cadila)
- Doxorubicin (Hetero Healthcare)
(Availability may vary depending on country regulations and supply)
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