Olvorin Leucovorin 300 mg Injection
Olvorin Leucovorin 300 mg Injection is a high-strength formulation used in oncology and emergency supportive care. It contains Leucovorin Calcium (Folinic Acid), an active derivative of folic acid that plays a critical role in reducing the toxic effects of certain chemotherapy drugs while also enhancing their therapeutic efficacy. This injection is commonly used in hospitals for rapid and effective management of chemotherapy-related complications.
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Composition and Content
- Active Ingredient: Leucovorin Calcium
- Strength: 300 mg per vial
- Dosage Form: Injection (IV/IM use)
- Category: Folate analog / Chemotherapy adjunct / Antidote
How to Use
- Administered by a qualified healthcare professional only
- Given via intravenous (IV) or intramuscular (IM) route
- Often used in hospital or clinical oncology settings
- Must follow strict timing when used with chemotherapy drugs
Dosage
- Dosage varies depending on indication and patient condition
- Commonly used in high-dose regimens for Methotrexate rescue
- May be given at regular intervals (e.g., every 6 hours) depending on toxicity levels
- Always administered under oncologist supervision
Uses and Treatments
Olvorin Leucovorin Injection is used for:
- Methotrexate toxicity (rescue therapy)
- Colorectal cancer treatment (with Fluorouracil)
- Overdose management of folic acid antagonists
- Supportive therapy in cancer treatment
- Certain cases of severe folate deficiency
Advantages
- Rapid action due to injectable form
- Effective in emergency toxicity management
- Enhances chemotherapy effectiveness
- Protects healthy cells from damage
- Trusted in advanced oncology protocols
Storage Conditions
- Store at controlled room temperature (15°C to 25°C)
- Protect from light and moisture
- Do not freeze
- Keep out of reach of children
Alternative Indian Brands for Leucovorin Injection
Some alternative brands available in India include:
- Leucovorin Calcium Injection IP (various generics)
- Folinic Acid Injection by multiple manufacturers
- Rescuvolin Injection
- Calcium Folinate Injection (Indian brands)
(Always consult a healthcare professional before switching brands.)
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