FURMECIL Gimeracil (5.8 mg) + Oteracil (15.8 mg) + Tegafur (15 mg) Capsules
FURMECIL Capsules are a combination oral chemotherapy medicine containing Tegafur, Gimeracil, and Oteracil. This combination is designed to enhance the effectiveness of fluoropyrimidine-based chemotherapy while reducing gastrointestinal toxicity. It is commonly used in the treatment of various solid tumors, especially gastrointestinal cancers.
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Composition and Content
Each capsule contains:
- Tegafur – 15 mg (prodrug of 5-FU, anticancer agent)
- Gimeracil – 5.8 mg (inhibits breakdown of 5-FU, enhancing efficacy)
- Oteracil – 15.8 mg (reduces gastrointestinal side effects)
- Dosage Form: Oral capsules
- Category: Antineoplastic / chemotherapy combination
How It Works
- Tegafur converts into 5-fluorouracil (5-FU) in the body, which inhibits cancer cell growth.
- Gimeracil prevents rapid degradation of 5-FU, increasing its therapeutic effect.
- Oteracil limits toxicity in the gastrointestinal tract, improving tolerability.
Together, they provide a balanced and effective chemotherapy regimen.
Uses and Treatments
FURMECIL Capsules are prescribed for:
- Gastric (stomach) cancer
- Colorectal cancer
- Pancreatic cancer
- Other gastrointestinal tumors (as advised by oncologists)
Dosage and How to Use
- Use only under strict medical supervision
- Dosage depends on body surface area (BSA) and patient condition
- Typically taken twice daily after meals
- Swallow capsules whole with water
- Follow treatment cycles as prescribed by the oncologist
⚠️ Regular monitoring (blood counts, liver and kidney function) is essential during therapy.
Advantages
- Combination therapy improves effectiveness of chemotherapy
- Reduced gastrointestinal toxicity compared to traditional 5-FU therapy
- Oral administration (no need for IV infusion)
- Better patient compliance and convenience
- Widely used in modern oncology protocols
Storage Conditions
- Store at room temperature (15°C to 25°C)
- Protect from light and moisture
- Keep out of reach of children
- Do not use after expiry
Alternative Indian Brands
Some alternative brands with similar composition include:
- S-1 Capsules (Tegafur + Gimeracil + Oteracil combinations)
- Tegafur-based combination generics available in India
(Always consult a healthcare professional before switching brands.)
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