Celginase L-Asparaginase 10,000 IU Injection
Introduction
Celginase L-Asparaginase 10000 IU Injection is an anti-cancer medication primarily used in the treatment of certain types of blood cancers. It belongs to a class of drugs known as enzymes that work by depriving cancer cells of essential nutrients required for their growth.
It is commonly prescribed as part of combination chemotherapy regimens, especially in pediatric and adult oncology.
Composition & Content
- Active Ingredient: L-Asparaginase
- Strength: 10,000 IU per vial
- Form: Lyophilized powder for injection (to be reconstituted before use)
How It Works
Cancer cells (especially leukemia cells) cannot produce the amino acid asparagine. This medicine breaks down asparagine in the bloodstream, effectively starving cancer cells and stopping their growth.
How to Use
- Administered only under medical supervision
- Given as:
- Intramuscular (IM) injection
- Intravenous (IV) infusion (depending on protocol)
- Reconstitution must be done using sterile water or saline as directed
⚠️ Should only be handled by trained healthcare professionals in a clinical setting.
Dosage
- Dosage depends on:
- Patient’s age and weight
- Type of cancer
- Treatment protocol
Typical Range:
- 6,000 IU to 10,000 IU/m² body surface area
- Frequency varies (daily, alternate days, or weekly cycles)
⚠️ Always follow oncologist’s prescription.
Uses
Celginase is widely used in treating:
- Acute Lymphoblastic Leukemia (ALL) – primary indication
- Lymphoblastic lymphoma
- Certain other hematologic malignancies (off-label use)
Treatment Role
- Used in induction therapy to achieve remission
- Combined with other chemotherapy drugs like:
- Vincristine
- Prednisone
- Methotrexate
It enhances the effectiveness of multi-drug cancer therapy.
Advantages
✔ Highly effective in leukemia treatment
✔ Selectively targets cancer cells
✔ Improves remission rates in ALL patients
✔ Essential part of pediatric oncology protocols
✔ Can be used in combination regimens
Storage Conditions
- Store at 2°C to 8°C (Refrigerated)
- Do not freeze
- Protect from light
- Use immediately after reconstitution or as directed
- Keep out of reach of children
Alternative Indian Brands
Here are some commonly available alternatives with the same composition:
- Leunase Injection
- Onconase Injection
- Asparaginase Medac
- Elspar Injection
- Kidrolase Injection
⚠️ Availability may vary; consult your supplier or oncologist.
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Conclusion
Celginase L-Asparaginase 10,000 IU Injection is a vital anti-cancer drug widely used in leukemia treatment. Its targeted mechanism, effectiveness in combination therapy, and proven clinical benefits make it an essential component of oncology care. Always use under medical supervision and source from trusted exporters like GlobMedIndia for quality assurance.
Contact Details
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📧 Email: info@globmedindia.com
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