PEMETREX Pemetrexed 500 MG Injection
PEMETREX Pemetrexed 500 MG Injection is a chemotherapy medication containing Pemetrexed, widely used in the treatment of certain types of cancer, especially lung cancer and mesothelioma. It belongs to a class of drugs known as antimetabolites, which work by interfering with the growth of cancer cells and slowing their spread in the body.
Pemetrexed disrupts essential cellular processes needed for DNA and RNA synthesis, thereby preventing cancer cells from multiplying. It is often used either alone or in combination with other chemotherapy drugs depending on the patient’s condition and cancer stage.
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Composition and Content
Active Ingredient: Pemetrexed Disodium
Strength: 500 mg per vial
Form: Lyophilized powder for injection
Category: Anticancer / Antimetabolite
How to Use
Administered as an intravenous (IV) infusion by a qualified healthcare professional.
Usually given in a hospital or oncology clinic setting.
Patients are often prescribed folic acid and vitamin B12 supplements to reduce side effects.
Pre-medication with corticosteroids may also be required.
Dosage
Typical dose: 500 mg/m² body surface area, given once every 21 days (one cycle).
Dose adjustments may be required based on:
Kidney function
Blood counts
Patient tolerance
Note: Always follow the oncologist’s prescription strictly.
Uses
PEMETREX Pemetrexed Injection is used in the treatment of:
Non-Small Cell Lung Cancer (NSCLC)
Malignant Pleural Mesothelioma
It may be used:
As first-line therapy (with platinum-based drugs)
As maintenance therapy
As second-line treatment
Treatments (Therapeutic Applications)
Combination therapy with Cisplatin for advanced lung cancer
Maintenance therapy in patients with stable disease
Treatment of mesothelioma in unresectable cases
Advantages
Targets cancer cells specifically by blocking multiple enzymes
Effective in both first-line and maintenance settings
Generally better tolerated than many traditional chemotherapies
Can improve survival rates in advanced lung cancer
Storage Conditions
Store below 25°C
Keep in a dry place, away from direct sunlight
Do not freeze
Keep out of reach of children
Reconstituted solution should be used immediately or as directed
Alternative Indian Brands for Pemetrexed 500 MG Injection
Some commonly available alternatives include:
Alimta 500 mg Injection (by Eli Lilly and Company)
Pemnat 500 mg Injection (by Natco Pharma)
Pemetrex 500 mg Injection (by Dr. Reddy's Laboratories)
Pemgem 500 mg Injection (by Hetero Healthcare)
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